The dosimetric impact of seroma volume changes over the course of radiotherapy treatment on sequential boost planning (Arm I) and a comparison of two concurrent hypofractionated boost methods (Arm II) for breast cancer patients eligible for RTOG protocol

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چکیده

Breast conserving surgery with adjuvant radiation therapy is supported by mult iple clinical t rials as being a safe alternative to total mastectomy. 2 Outlined by Arm I of RTOG Protocol 1005, 1 one current standard of care for external beam radiation (EBRT) is delivery of 50 Gray (Gy) in 25 fract ions to the whole breast with a sequential 12 Gy photon or electron boost to the post-lumpectomy bed delivered in 6 fractions. The addition of such a tumor bed boost has shown to further decrease recurrence rates for patients with invasive breast cancer. 3

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تاریخ انتشار 2013